Oligonucleotide
NCEs

The demand for oligonucleotide therapeutics is booming

Emerging as a new treatment option in rare and orphan disease areas, oligonucleotide therapeutics have matured into a drug class with a broad indication spectrum. The promise of oligonucleotides is making a difference to an increasing number of patients. If you have the products to give patients hope, we can help you get them to market – quickly.

Let’s build a new future in oligonucleotides

If you’ve developed a useful oligonucleotide, you’ll know just how exciting the possibilities are. But to realize those possibilities, you need expertise in process development, GMP manufacturing and meeting regulations. That’s where we can help.

We bring innovation and decades of experience to every stage of the process, boosting your product’s potential with new engineering solutions for tight process control and high throughput and we can get your product to market!

GMP oligonucleotide manufacturer

As a GMP (Good Manufacturing Practice) oligonucleotide manufacturer, we guarantee that the production of oligonucleotides adheres to the highest quality standards, ensuring purity, consistency, and safety. We follow strict regulatory guidelines to ensure that oligonucleotides meet the necessary requirements for clinical and therapeutic use, offering reliability and compliance with industry standards at every stage of the production process.

Perfect your oligonucleotide drug

Working with us, you’ll have an exceptional analytical chemistry team on board. Our team has vast experience in developing and validating test methods for large and structurally complicated molecules. Not to mention their expertise in solid-phase synthesis, protecting group chemistry, purification by chromatography, ultra/diafiltration techniques, precipitation and lyophilization.

Your products will feel the full benefit of our advanced chemistry, manufacturing, and control (CMC) development services for oligonucleotide-based APIs. It starts with the establishment of scalable manufacturing processes. And it ends with IND and NDA applications supported by our in-house regulatory affairs specialists.

Avoid the risks associated with clinical and commercial milestones. We’ll create a straightforward plan for getting your oligonucleotides to market.

A focus on sustainability within oligonucleotide manufacturing

Sustainability is becoming increasingly important in oligonucleotide manufacturing. Manufacturers are exploring eco-friendly methods to reduce waste, energy consumption, and the environmental impact of production processes. This includes implementing green chemistry principles, improving resource efficiency, and adopting sustainable packaging. A focus on sustainability not only helps minimize the ecological footprint but also aligns with global efforts to promote responsible manufacturing in the pharmaceutical industry. This is why for Bachem, sustainability is more than a duty; it is a fundamental part of our strategic foundation.

Get some more details on our oligonucleotide services

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Why work with us?

Capacity – Rapid implementation of manufacturing capacities for oligo-based APIs
Excellence – We offer the highest quality products and services in the industry, with broad knowledge and expertise in peptide development and production.
Internationally approved – Our facilities are regularly inspected by the FDA, Swissmedic and other prominent regulatory authorities – and we’re fully GMP compliant
Expertise – Our people are highly skilled and passionate about emerging technologies, but also pride themselves on being reliable and committed to customers.
Sustainability – We’re convinced that ethical behavior and integrity are essential for long-term business success, so we’re focused on improving our social, economic and environmental sustainability.

The future of oligonucleotide manufacturing

Learn more about stirred-bed synthesis and the advantages for large-scale production.

Read our white paper

Inquire about the oligonucleotide facility tour

What our customers are saying

"Theratechnologies is very pleased to be working with Bachem as a supplier of Tesamorelin. The experience has been very collaborative and contributed to the success of the development program all the way up to market approval. Certainly, Bachem's expertise in peptides, their professional project management and dedication to quality gives us great confidence in knowing we are with the right partner."

- Pierre Perazzelli, V.P. Pharmaceutical Development, Theratechnologies, Inc.

“Bachem is a strategic partner for all Polyphor programs including high quality large scale production of Balixafortide (POL6326) which we are advancing in a Phase III trial in combination with eribulin in patients with advanced breast cancer. Bachem’s collaborative approach with long term “win-win” business mindset and excellent project management gives us confidence for the future of our programs.”